產(chǎn)品編號(hào) | bs-8246R-BF488 |
英文名稱 | Rabbit Anti-CADM2/BF488 Conjugated antibody |
中文名稱 | BF488標(biāo)記的細(xì)胞粘附分子2抗體 |
別 名 | CADM2; CADM2_HUMAN; Cell adhesion molecule 2; IgSF4D; Immunoglobulin superfamily member 4D; NECL 2; Necl 3; NECL-3; NECL2; Necl3; Nectin like protein 3; Nectin-like protein 3; synCAM 2; synCAM2. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 細(xì)胞粘附分子 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 45kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CADM2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF4D (Ig superfamily member 4D) is also known as CADM2 (cell adhesion molecule 2), Necl-3 (nectin-like protein 3) or synCAM2 and is a 435 amino acid protein that is a member of the nectin family. IGSF4D contains two C2-type domains and one V-type domain, which are characteristic of the nectin family and are thought to function in molecular recognition. IGSF4D is expressed in many tissues, including brain, where it is detected in the nervous system, specifically in myelinated axons and ependymal cells. IGSF4D is localized to the plasma membrane as a single-pass membrane protein and is expressed as three isoforms. IGSF4D functions in the regulation of cell–cell adhesion by homophilic and heterophilic interactions leading to cell aggregation. These interactions are also important for neuron–neuron or neuron–glia associations, which are important for the development and function of the central nervous system. IGSF4D is downregulated in lung cancer, suggesting a possible role in tumor suppression. Function: Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Cell projection, axon. Note=Found in the axoplasm of myelinated axons. Similarity: Belongs to the nectin family. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain. Database links: UniProtKB/Swiss-Prot: Q8N3J6.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 在线播放一区二区三区 | 欧美一级婬片A片免费放上海宾馆 | 激情69蜜桃一区二区三区 | 少妇被猛烈进入免费视频 | 午夜福利伦伦电影理论片2021 | 91在线午夜福利精品 | 成人性生活视频免费观看 | 很很操狠狠爱很很鲁 | 国产区精品福利在线熟女 | 白大乳大jb内射网站 | 17.c 蜜桃视频 红桃视频 | 蜜桃在线码无精品秘入口九色 | 爱欲AV无码专区在线 | 亚洲免费在线观看 | 男女动态图一区二区无码 | 国产熟妇婬乱一区二区 | 日本黄A级A片国产免费 | 国产精品一级毛片A片骨灰盒 | 亚洲啪AV永久无码精品放毛片 | 国产一级做a爱免费高潮小说 | 日韩黄色视频免费播放 | 国产精品91网在线观看 | 山村老骚乱老女人A片 | 亂倫近親相姦中文字幕完整片 | 一级a片免费视频在线观看 91无码国产色情在线观看 | 久久久精品理论A级A片 | 特级毛片片A片AAAAAA | 五十路熟妇亲子交尾在线视频 | 性感美女电影院在线观看 | 91欧美精品成人AAA片 | 免费看无码一级A片放24小时 | 免费一看一级毛片少妇丰满 | 亚洲AⅤ无码一级毛片孕交 成人午夜精品一区二区三区 | 综合久久,综合色蜜桃 | 国产无码电影在线观看 | 欧美成人影片在线观看 | 白丝女仆被 免费无遮挡 | 黄色视频网站免费在线观看 | 国产裸体美女永久免费无遮挡 | 国产裸体不遮挡视频网站 |