强伦轩一级A片在线观看,中文字幕乱码人妻二区三区,鲁鲁狠狠狠7777一区二区,西西4444www无码精品
掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产小电影在线观看,www.84成人A片
Rabbit Anti-Phospho-ELk1(Thr417)/Cy7 Conjugated antibody (bs-5336R-Cy7)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-5336R-Cy7
英文名稱 Rabbit Anti-Phospho-ELk1(Thr417)/Cy7 Conjugated antibody
中文名稱 Cy7標(biāo)記的磷酸化細(xì)胞轉(zhuǎn)錄因子ELK1抗體
別    名 ELK1 (phospho T417); Elk-1(Phospho-Thr417); p-ELK1 (T417); p-Elk-1(Thr417); ELK 1; ELK1 member of ETS oncogene family; ELK1 protein; ELK2 member of ETS oncogene family; ETS domain containing protein Elk 1; ETS domain containing protein Elk1; ETS domain protein Elk1; Oncogene Elk1; ETS domain-containing protein Elk-1 isoform a; ETS domain-containing protein Elk-1; ETS-like gene 1; tyrosine kinase (ELK1) oncogene; ELK1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  生長(zhǎng)因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Guinea Pig, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human ELk1 around the phosphorylation site of Thr417 [LS(p-T)PV]
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012].

Function:
Stimulates transcription. Binds to purine-rich DNA sequences. Can form a ternary complex with the serum response factor and the ETS and SRF motifs of the fos serum response element.

Subunit:
Interacts in its sumoylated form with PIAS2/PIASX which enhances its transcriptional activator activity. Interacts with MAD2L2; the interaction is direct and promotes phosphorylation by the kinases MAPK8 and/or MAPK9.

Subcellular Location:
Nucleus.

Tissue Specificity:
Lung and testis.

Post-translational modifications:
Sumoylation represses transcriptional activator activity as it results in recruitment of HDAC2 to target gene promoters which leads to decreased histone acetylation and reduced transactivator activity. It also regulates nuclear retention.
On mitogenic stimulation, phosphorylated on C-terminal serine and threonine residues by MAPK1. Ser-383 and Ser-389 are the preferred sites for MAPK1. In vitro, phosphorylation by MAPK1 potentiates ternary complex formation with the serum responses factors, SRE and SRF. Also phosphorylated on Ser-383 by MAPK8 and/or MAKP9. Phosphorylation leads to loss of sumoylation and restores transcriptional activator activity. Phosphorylated and activated by CAMK4, MAPK11, MAPK12 and MAPK14.

Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.

Database links:

Entrez Gene: 1978 Human

Entrez Gene: 13685 Mouse

Entrez Gene: 116636 Rat

Omim: 602223 Human

SwissProt: Q13541 Human

SwissProt: Q60876 Mouse

SwissProt: Q62622 Rat

Unigene: 411641 Human

Unigene: 6700 Mouse

Unigene: 11161 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.nmgps.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
亚洲无码视频在线观看 | 免费无码婬片AAAA国产 | 成人精品在线视频 | 国产扒老师丝袜在线观看 | 农村老女人A片免费播放 | 黃色A片老师三級三級三級H野外 | 免费av百万久久 | 第一福利丝瓜AV导航 | 寡妇高潮一级毛片免费看 | 色欲午夜性一二三区熟女 | 久久成人麻豆精品一牛影视 | 性猛交AAAA片免费观看直播 | 免费黄色视频在线观看一区二区 | 成年人免费视频麻豆 | 麻豆网站少妇AAA片 一区二区成人色情网站 | 四川BBBB搡BBB搡B1图 | 波多野吉衣成人在线 | AV成人一区二区三区 | 久久国产Av无码一区二区 | 国产精品久久久久久久不卡 | 日本久久免费一二三四区 | 欧美 国产 亚洲视频 | 国产电影一区二区三区 | 亚洲精品无码久久久久苍井空国产一 | 99热这里只有精品99 | 午夜免费九九九九 | 无码人妻熟妇av又粗又大 | 国产BBB搡BBB爽爽爽电影 | 国产一区二区视频在线观看 | 国产成人AV一区二区三区在线观看 | 户外露出自慰一区二区 | 国产无遮无挡120秒 中文字幕乱码视频播放 | 中国少妇自慰成人A片 | 久久国产精品波多野结衣无码电影 | 国产做受6高潮A片91 | 色情午夜 码一区二区 | 久久丫不卡人妻内射中出 | 国产又粗又猛又黄视频 | 精品毛片一区二区看A片 | 真实的国产乱XXXX | 国产成人精品女人久久久 |