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Rabbit Anti-ITPR2/BF350 Conjugated antibody (bs-4243R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4243R-BF350
英文名稱 Rabbit Anti-ITPR2/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的5-三磷酸肌醇受體2抗體
別    名 4; 5-trisphosphate receptor; Inositol 1 4 5 trisphosphate receptor type 2; Inositol 1,4,5-trisphosphate receptor type 2; Inositol 145 trisphosphate receptor type 2; InsP3 R2; InsP3R2; IP3 R2; IP3 receptor isoform 2; IP3R 2; IP3R2; ITPR 2; Itpr2; ITPR2_HUMAN; Type 2 inositol 1 4 5 trisphosphate receptor; Type 2 inositol 1; Type 2 inositol 145 trisphosphate receptor; Type 2 InsP3 receptor.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Cow, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 308kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ITPR2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.

Function:
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity).

Subunit:
Homotetramer. Interacts with CABP1.

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.

Tissue Specificity:
Isoform Short is found in skeletal muscle and heart.

Post-translational modifications:
Phosphorylation by cAMP-dependent PKA on Ser-937 increases calcium release.

Similarity:
Belongs to the InsP3 receptor family.
Contains 5 MIR domains.

Database links:

Entrez Gene: 281878 Cow

Entrez Gene: 3709 Human

Entrez Gene: 16439 Mouse

Entrez Gene: 81678 Rat

Omim: 600144 Human

SwissProt: Q8WN96 Cow

SwissProt: Q14571 Human

SwissProt: Q9Z329 Mouse

SwissProt: P29995 Rat

Unigene: 512235 Human

Unigene: 393003 Mouse

Unigene: 7800 Mouse

Unigene: 89152 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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