產(chǎn)品編號 | bs-4205R-HRP |
英文名稱 | Rabbit Anti-hnRNP F/HRP Conjugated antibody |
中文名稱 | 辣根過氧化物酶標(biāo)記的異質(zhì)核糖核蛋白F抗體 |
別 名 | Heterogeneous nuclear ribonucleoprotein F; Heterogeneous nuclear ribonucleoprotein F; hnRNP F; HNRNPF; hnRP F; hnRPF; mcs94 1; MGC110997; Nucleolin like protein; Nucleolin like protein mcs94 1; OK/SW cl.23; Ribonucleoprotein F; HNRPF_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 染色質(zhì)和核信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, Rat, (predicted: Human, Dog, Pig, Rabbit, ) |
產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 46kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human hnRNP F |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: hnRNP F is part of the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. hnRNP F binds to RNAs which have guanosine-rich sequences. Function: Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state. Subunit: Identified in the spliceosome C complex. Interacts with AGO1, AGO2, TBP and TXNL4/DIM1. Subcellular Location: Nucleus, nucleoplasm. Tissue Specificity: Expressed ubiquitously. Post-translational modifications: Sumoylated. Similarity: Contains 3 RRM (RNA recognition motif) domains. Database links: Entrez Gene: 3185 Human Entrez Gene: 98758 Mouse Omim: 601037 Human SwissProt: P52597 Human SwissProt: Q9Z2X1 Mouse Unigene: 712955 Human Unigene: 808 Human Unigene: 422979 Mouse Unigene: 476420 Mouse Unigene: 144596 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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