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Rabbit Anti-CIAPIN1/Cy5.5 Conjugated antibody (bs-5764R-Cy5.5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-5764R-Cy5.5
英文名稱 Rabbit Anti-CIAPIN1/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標(biāo)記的細(xì)胞因子誘導(dǎo)凋亡抑制因子1
別    名 Anamorsin; CIAPIN 1; Cytokine induced apoptosis inhibitor 1; DRE2; CPIN1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  細(xì)胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CIAPIN1 (101-200aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
CIAPIN1 (Cytokine induced apoptosis inhibitor 1) expression is dependent on growth factor stimulation. Overexpression confers resistance to apoptosis caused by IL3 deprivation. It may be required during hematopoiesis to mediate antiapoptotic effects of various cytokines. It also confers multidrug resistance in gastric cancer cells by upregulating the expression of MDR1 and MRP1.

Function:
May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity).

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitously expressed. Highly expressed in heart, liver and pancreas.

Similarity:
Belongs to the anamorsin family.

Database links:

Entrez Gene: 57019 Human

Entrez Gene: 109006 Mouse

Omim: 608943 Human

SwissProt: Q6FI81 Human

SwissProt: Q8WTY4 Mouse

Unigene: 4900 Human

Unigene: 27582 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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