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Rabbit Anti-5HT7 Receptor/APC Conjugated antibody (bs-12056R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12056R-APC
英文名稱 Rabbit Anti-5HT7 Receptor/APC Conjugated antibody
中文名稱 APC標記的5-羥色胺受體7抗體
別    名 SR-7; HT 7; 5 HT X; 5 hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase coupled); 5 hydroxytryptamine (serotonin) receptor 7; 5 hydroxytryptamine receptor 7; 5-HT-7; 5-HT-X; 5-HT7; 5-hydroxytryptamine receptor 7; 5HT7; 5HT7R_HUMAN; HTR7; Serotonin 5 HT 7 receptor; Serotonin receptor 7.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經生物學  細胞膜受體  G蛋白偶聯(lián)受體  新陳代謝  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human 5HT7 Receptor/SR-7
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]

Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Isoform A is the predominant isoform in spleen, caudate and hippocampus.
Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 3363 Human

Entrez Gene: 15566 Mouse

Entrez Gene: 65032 Rat

Entrez Gene: 100135549 Guinea pig

Omim: 182137 Human

SwissProt: P50407 Guinea pig

SwissProt: P34969 Human

SwissProt: P32304 Mouse

SwissProt: P32305 Rat

Unigene: 73739 Human

Unigene: 254266 Mouse

Unigene: 87132 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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