產(chǎn)品編號 | bs-13961R-Bio |
英文名稱 | Rabbit Anti-SLC44A4/Biotin Conjugated antibody |
中文名稱 | 生物素標(biāo)記的膽堿轉(zhuǎn)運(yùn)體樣蛋白4 |
別 名 | Solute carrier family 44, member 4; SLC44A4; CTL4; FLJ14491; NG22; CTL4_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 淋巴細(xì)胞 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Horse, ) |
產(chǎn)品應(yīng)用 | WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 79kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SLC44A4 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Choline is an essential nutrient that is required for the synthesis of both acetylcholine, a neurotransmitter found in cholinergic nerve terminals, and phosphatidylcholine, a key component of cell membranes. Choline deficiencies are associated with defects in cell growth and have been implicated in disorders such as Alzheimer’s and Parkinson’s disease. The choline transporter-like protein family (CTL) are solute carriers that transport choline, a compound which is not able to permeate cells, across the cell membrane. CTL4, also known as SLC44A4 (Solute carrier family 44 member 4), is a multi-pass membrane protein which can fuse with Neu1, generating a CTL4-Neu1 transcript. This fusion is implicated in sialidosis, a disease characterized by improper lysosomal storage. Subcellular Location: Membrane; Multi-pass membrane protein (By similarity). DISEASE: Note=An interstitial deletion causing the fusion of exon 10 of CTL4 with the 3'-UTR of NEU has been detected in two patients affected by sialidosis. Similarity: Belongs to the CTL (choline transporter-like) family. Database links: UniProtKB/Swiss-Prot: Q53GD3.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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