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Rabbit Anti-Density Regulated Protein/BF488 Conjugated antibody (bs-14276R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-14276R-BF488
英文名稱 Rabbit Anti-Density Regulated Protein/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的密度調(diào)節(jié)蛋白抗體
別    名 denr; DENR_HUMAN; Density regulated protein; Density-regulated protein; DRP; DRP1; DRP1 protein; Protein DRP1; SMAP-3; SMAP3; Smooth muscle cell associated protein 3; Smooth muscle cell-associated protein 3.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  轉(zhuǎn)運(yùn)蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Density Regulated Protein
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008]

Function:
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.

Tissue Specificity:
Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney.

Similarity:
Belongs to the DENR family.
Contains 1 SUI1 domain.

Database links:

Entrez Gene: 8562 Human

Entrez Gene: 771794 Chicken

Entrez Gene: 614238 Cow

Entrez Gene: 68184 Mouse

Entrez Gene: 360806 Rat

Entrez Gene: 444615 Xenopus laevis

Omim: 604550 Human

SwissProt: Q5ZJ39 Chicken

SwissProt: Q2HJ47 Cow

SwissProt: O43583 Human

SwissProt: Q9CQJ6 Mouse

SwissProt: Q6GLZ1 Xenopus laevis

SwissProt: Q6DFN7 Xenopus tropicalis

Unigene: 22393 Human

Unigene: 28549 Mouse

Unigene: 7540 Xenopus laevis



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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