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Rabbit Anti-BDP/BF594 Conjugated antibody (bs-12580R-BF594)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12580R-BF594
英文名稱 Rabbit Anti-BDP/BF594 Conjugated antibody
中文名稱 BF594標記的神經(jīng)母細胞瘤相關(guān)蛋白ARID3B抗體
別    名 BDP / ARID3B; ARI3B_HUMAN; ARID domain containing protein 3B; ARID domain-containing protein 3B; Arid3b; AT rich interactive domain 3B BRIGHT like; AT rich interactive domain containing protein 3B; AT-rich interactive domain-containing protein 3B; Bright and dead ringer gene product homologous protein Bdp; Bright and dead ringer protein; Bright like; Bright-like protein; Brightlike; DRIL2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  干細胞  細胞周期蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BDP/ARID3B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma.

Function:
Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A.

Subunit:
Heterodimer with ARID3A. Interacts with unphosphorylated RB1.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K562 erythrocytic leukemia cells (at protein level).

Similarity:
Contains 1 ARID domain.
Contains 1 REKLES domain.

Database links:

Entrez Gene: 56380 Mouse

Entrez Gene: 367092 Rat

SwissProt: Q9Z1N7 Mouse

Unigene: 425588 Mouse

Unigene: 18259 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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