產(chǎn)品編號 | bs-13158R-APC |
英文名稱 | Rabbit Anti-FHOD1/APC Conjugated antibody |
中文名稱 | APC標(biāo)記的肢體畸形相關(guān)蛋白FHOD1抗體 |
別 名 | FH1/FH2 domain containing protein; FH1/FH2 domain-containing protein 1; Fhod1; FHOD1_HUMAN; FHOS; FHOS1; Formin homolog overexpressed in spleen 1; Formin homology 2 domain containing 1; Formin homology 2 domain containing protein 1; Formin homology 2 domain-containing protein 1. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 信號轉(zhuǎn)導(dǎo) 細(xì)胞骨架 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 126kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FHOD1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of protein products known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing actin filament assembly. The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. FHOD1 induces the formation of and associates with bundled actin stress fibers in response to the activity of the Rho-ROCK cascade. It influences several cellular activities including cell migration, cytoskeletal arrangement, signal transduction and gene expression. Function: Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Subunit: Self-associates via the FH2 domain. Binds to F-actin via its N-terminus. Binds to the cytoplasmic domain of CD21 via its C-terminus. Interacts with ROCK1 in a Src-dependent manner. Subcellular Location: Cytoplasm. Cytoplasm; cytoskeleton. Predominantly cytoplasmic. Tissue Specificity: Ubiquitous. Highly expressed in spleen. Post-translational modifications: Phosphorylated by ROCK1. Similarity: Belongs to the formin homology family. Contains 1 FH1 (formin homology 1) domain. Contains 1 FH2 (formin homology 2) domain. Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. Database links: UniProtKB/Swiss-Prot: Q9Y613.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 日本人做爰毛片免费播 | 99国产精品免费视频观看 | 一级老太婆毛片免费播放 | 特黄AAAAAAAAA真人 | 国产欧美综合一区二区三区 | 国产综合在线视频 | 少妇人妻一级A毛片无码 | 超碰91人人做人人爱少妇 | 免费看黃色三級三級视 | 久久精品欧美一区二区三区不卡 | 中文字幕乱码人妻无码久久竹菊 | 久久国产精品色AV免费观看 | 国产精品成人在线 | G·G视频最新地址在线观看 | 91人人网人人操人人爽 | 欧美一级婬片A片免费手机版 | 国产又粗又黄又爽又硬的蘑菇 | 国产一国产精品一级毛片 | 精品传媒一区二区三区A片 国产suv精品一区二区 | 黄色小视频在线免费观看 | 91无码粉嫩小泬无套在线哈尔滨 | 在线亚洲免费免费 | av一级毛片高清 | 亂倫國產一級生活片免費 | 日本丰满少妇一区二区三区 | 蜜臀av伊在人亚洲香蕉才情品区 | 性感丰满爆乳少妇无码中出福利视频 | ThePorn国产入口 | 国产日韩精品无码去免费专区国产 | 高潮丰满极品乱伦 | 亚洲无码分区精品视频 | 四季无码AV在线播放播放 | 国产黃色A片三級熟女 | 国产精品欲AV蜜臀 | 人与禽一级婬片A片69式按摩 | 波多野结衣结衣无码视频在线播放 | 人人妻人人澡爽DVD盘锦 | 精品人妻一区二区三区密桃 | av无码在线播放 | 国产精品爽爽久久久久久蜜臀 |