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Rabbit Anti-GBP4/Gold Conjugated antibody (bs-13303R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-13303R-Gold
英文名稱 Rabbit Anti-GBP4/Gold Conjugated antibody
中文名稱 膠體金標記的G蛋白結合蛋白4抗體
別    名 GBP 4; GBP-4; GBP4; GBP4_HUMAN; GTP binding protein 4; GTP-binding protein 4; Guanine nucleotide binding protein 4; Guanine nucleotide-binding protein 4; Guanylate binding protein 4; Guanylate-binding protein 4; Mpa2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  神經(jīng)生物學  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 73kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GBP4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
GBP4 is a 640 amino acid protein that localizes to the cytoplasm and belongs to the guanylate binding protein (GBP) family. Like other GBP proteins, GBP4 contains a conserved N-terminal GTP-binding domain and functions to bind and hydrolyze GTP, GDP and GMP, possibly playing a role in erythroid differentiation. The gene encoding GBP4 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Function:
Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the GBP family.

Database links:
UniProtKB/Swiss-Prot: Q96PP9.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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