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Rabbit Anti-VAMP1+VAMP2+VAMP3/BF488 Conjugated antibody (bs-10427R-BF488)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-10427R-BF488
英文名稱 Rabbit Anti-VAMP1+VAMP2+VAMP3/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的囊泡相關(guān)膜蛋白1,2,3抗體
別    名 VAMP-1+2+3; Vesicle Associated Membrane Protein 1; DKFZp686H12131; SYB 1; SYB1; Synaptobrevin 1; Synaptobrevin1; Synaptobrevin-1; VAMP 1; VAMP-1; Vesicle associated membrane protein 1; Vesicle associated membrane protein 1 synaptobrevin 1; VAMP1_HUMAN; Vesicle-associated membrane protein 1; Vesicle Associated Membrane Protein 2; FLJ11460; RATVAMPB; RATVAMPIR; SYB; SYB2; Synaptobrevin 2; VAMP 2; VAMP-2; Vesicle associated membrane protein 2; Vesicle-associated membrane protein 2; VAMP2_HUMAN; Synaptobrevin-2; Vesicle Associated Membrane Protein 3; VAMP-3; VAMP 3; VAMP3; CEB; Cellubrevin; Synaptobrevin 3; Synaptobrevin-3; MGC108618; Vamp3; D130027G05Rik; VAMP3_HUMAN; Vesicle-associated membrane protein 3.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VAMP-1+2+3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008].

Function:
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.

Subunit:
Interacts with VAPA and VAPB.

Subcellular Location:
Membrane; Single-pass type IV membrane protein (Probable). Cell junction, synapse, synaptosome.

Tissue Specificity:
Nervous system, skeletal muscle and adipose tissue.

Similarity:
Belongs to the synaptobrevin family.
Contains 1 v-SNARE coiled-coil homology domain.

Database links:

Entrez Gene: 6843 Human

Entrez Gene: 6844 Human

Entrez Gene: 9341 Human

Entrez Gene: 22317 Mouse

Entrez Gene: 22318 Mouse

Entrez Gene: 22319 Mouse

Entrez Gene: 24803 Rat

Entrez Gene: 25624 Rat

Entrez Gene: 29528 Rat

Omim: 185880 Human

Omim: 185881 Human

Omim: 603657 Human

SwissProt: P23763 Human

SwissProt: P63027 Human

SwissProt: Q15836 Human

SwissProt: P63024 Mouse

SwissProt: P63044 Mouse

SwissProt: Q62442 Mouse

SwissProt: P63025 Rat

SwissProt: P63045 Rat

SwissProt: Q63666 Rat

Unigene: 20021 Human

Unigene: 25348 Human

Unigene: 66708 Human

Unigene: 273930 Mouse

Unigene: 28643 Mouse

Unigene: 32321 Mouse

Unigene: 12939 Rat

Unigene: 219999 Rat

Unigene: 31977 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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