產(chǎn)品編號(hào) | bs-17105R-APC |
英文名稱 | Rabbit Anti-LARP6/APC Conjugated antibody |
中文名稱 | APC標(biāo)記的LARP6蛋白抗體 |
別 名 | Acheron; Achn; FLJ11196; La ribonucleoprotein domain family member 6; La-related protein 6; LARP6; LARP6_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 55kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human LARP6 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
Function: Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9. Subunit: Interacts (via the HTH domain) with VIM/vimentin.Interacts (via C-terminus) with non-muscle myosin MYH10. Interacts (via C-terminus) with DHX9. Subcellular Location: Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm. Tissue Specificity: Expressed in numerous tissues. Similarity: Contains 1 HTH La-type RNA-binding domain. Database links: Entrez Gene: 55323 Human Entrez Gene: 67557 Mouse Omim: 611300 Human SwissProt: Q9BRS8 Human SwissProt: Q8BN59 Mouse Unigene: 416755 Human Unigene: 44546 Mouse Unigene: 33750 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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