强伦轩一级A片在线观看,中文字幕乱码人妻二区三区,鲁鲁狠狠狠7777一区二区,西西4444www无码精品
掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲+小说+欧美+激情+另类,日本无码熟人中文字幕,国产中文字幕在线观看
Rabbit Anti-Ataxin 3/AP Conjugated antibody (bs-17208R-AP)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-17208R-AP
英文名稱(chēng) Rabbit Anti-Ataxin 3/AP Conjugated antibody
中文名稱(chēng) 堿性磷酸酶(AP)標(biāo)記的脊髓小腦性共濟(jì)失調(diào)蛋白3抗體
別    名 AT3; Ataxin 3; Ataxin-3; ATX3; ATX3_HUMAN; ATXN3; EC 3.4.22.; JOS; Josephin; Machado Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3); Machado Joseph disease; Machado Joseph disease protein 1; Machado-Joseph disease protein 1; Machado-Joseph disease protein 1 homolog; MJD; MJD gene; MJD1; Olivopontocerebellar ataxia 3; OTTHUMP00000221583; OTTHUMP00000221585; OTTHUMP00000221586; OTTHUMP00000221587; OTTHUMP00000231995; OTTHUMP00000231997; Rsca3; SCA3; SCA3 gene; Spinocerebellar ataxia type 3 protein.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  表觀遺傳學(xué)  泛素  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Ataxin 3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2009]

Function:
Interacts with key regulators (CBP, p300 and PCAF) of transcription and represses transcription. Acts as a histone-binding protein that regulates transcription. Acts as a deubiquitinating enzyme.

Subcellular Location:
Nucleus matrix. Predominantly nuclear, but not exclusively, inner nuclear matrix.

Tissue Specificity:
Ubiquitous.

DISEASE:
Defects in ATXN3 are the cause of spinocerebellar ataxia type 3 (SCA3) [MIM:109150]; also known as Machado-Joseph disease (MJD). Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA3 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. The molecular defect in SCA3 is the a CAG repeat expansion in ATXN3 coding region. Longer expansions result in earlier onset and more severe clinical manifestations of the disease.

Similarity:
Contains 1 Josephin domain.
Contains 3 UIM (ubiquitin-interacting motif) repeats.

Database links:

Entrez Gene: 4287 Human

Entrez Gene: 110616 Mouse

Entrez Gene: 60331 Rat

Omim: 607047 Human

SwissProt: P54252 Human

SwissProt: Q9CVD2 Mouse

SwissProt: O35815 Rat

Unigene: 532632 Human

Unigene: 271914 Mouse

Unigene: 42932 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.nmgps.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
91麻豆精品A片国产在线观看 | 久久国产乱子伦精品一区二区 | www.日韩欧美 | 精品无码国产污污污免费 | 国产精品久久久久久吹潮 | 日本无码白浆一区二区 | 亚洲小说欧美激情另类A片小说 | 国内精品久久久久久久影视简单 | 国产一区三区王色视频 | 裸体美女18禁免费看久久 | www.yw193.com | 涂了春药被一群人伦爽99式 | 国产小视频在线观看 | 中文字幕无码人妻少妇免费视频 | 噜噜噜噜噜噜av中文字幕 | 日韩午夜视频在线观看 | 亚洲精品中文字幕无码久久久久久 | 黄色高清视频在线观看 | 国产色欲婬乱免费视频高潮 | 国产毛片农村妇女系列bd | 色欲av永久无码精品无码蜜桃 | 一级做a爰片久久毛片潮喷无码 | 成人午夜婬片免费观看 | 成人午夜伦理福利电影 | 免费一级婬片A片AAA小说软件 | 无码成人AAAAA毛片 | 一本大道HEYZO无码中文字幕 | 日本无码狂肉中文字幕 | 91在线中文字幕人妻 | 91精品国产乱码久久久久 | 亚洲AV秘 无码一区花狩 | 国产综合在线视频 | 国内精品国产成人三级 | 国產又粗又猛又爽又黄 | 无套内射在线观看 | 女女同恋一区二区在线观看 | 国产女人成人精品A区 | 亚洲精品久久久久久久久豆 | 亚洲精品无码高清视频 | 午夜av日韩日逼网 | 女同亚洲精品一区二区三 |