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Rabbit Anti-OSBPL2/AP Conjugated antibody (bs-17517R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-17517R-AP
英文名稱 Rabbit Anti-OSBPL2/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的氧固醇結合蛋白樣2抗體
別    名 FLJ20223; KIAA0772; MGC4307; MGC8342; ORP2; OSBP related protein 2; Oxysterol binding protein like 2; Oxysterol binding protein related protein 2.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Pig, Cow, Horse, Sheep, )
產品應用 WB=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human OSBPL2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
This gene encodes a member of the oxysterol binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N terminal pleckstrin homology domain and a highly conserved C terminal OSBP like sterol binding domain, although some members contain only the sterol binding domain. This encoded protein contains only the sterol binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3 phosphate, but cannot bind to 25 hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.

Database links:

Entrez Gene: 9885 Human

Entrez Gene: 228983 Mouse

Entrez Gene: 296461 Rat

Omim: 606731 Human

SwissProt: Q9H1P3 Human

SwissProt: Q8BX94 Mouse

Unigene: 473254 Human

Unigene: 253578 Mouse

Unigene: 12390 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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