產(chǎn)品編號(hào) | bs-18050R-BF488 |
英文名稱(chēng) | Rabbit Anti-HMG20A/BF488 Conjugated antibody |
中文名稱(chēng) | BF488標(biāo)記的高遷移率族蛋白20A抗體 |
別 名 | FLJ10739; High mobility group 20A; High mobility group protein 20A; HM20A_HUMAN; HMG box containing protein 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain protein HMGX1; HMG domain-containing protein 1; HMG domain-containing protein HMGX1; hmg20a; HMGX1; HMGXB1; Hypothetical protein FLJ10739; iBRAF; Inhibitor of BRAF35. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, Rhesus monkey, Gorilla, Orangutan) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 40kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HMG20A |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
Function: Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Similarity: Contains 1 HMG box DNA-binding domain. Database links: Entrez Gene: 10363 Human Entrez Gene: 100061369 Horse Entrez Gene: 66867 Mouse Entrez Gene: 100448723 Orangutan Entrez Gene: 714893 Rhesus monkey Omim: 605534 Human SwissProt: Q9NP66 Human SwissProt: Q6NV87 Mouse SwissProt: Q9DC33 Mouse Unigene: 69594 Human Unigene: 744173 Human Unigene: 150856 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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