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Rabbit Anti-MMP21/RBITC Conjugated antibody (bs-18963R-RBITC)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-18963R-RBITC
英文名稱 Rabbit Anti-MMP21/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的基質(zhì)金屬蛋白酶21抗體
別    名 Matrix metalloproteinase 21; MIFR; MMP21_HUMAN; MMP 21.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Horse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MMP21
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the matrix metalloproteinase family. Proteins in this family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, and disease processes, such as asthma and tumor metastasis. The encoded protein may play an important role in embryogenesis, particularly in neuronal cells, as well as in lymphocyte development and survival. [provided by RefSeq, May 2013]

Function:
May have an important and specific function in tumor progression and embryogenesis. Cleaves alpha-1-antitrypsin.

Subcellular Location:
Secreted

Tissue Specificity:
Identified in fetal brain, kidney and liver. In adult tissues found primarily in ovary, kidney, liver, lung, placenta, brain and peripheral blood leukocytes. Expressed as well in various cancer cell lines.

Post-translational modifications:
The precursor is cleaved by a furin endopeptidase

Similarity:
Belongs to the peptidase M10A family.
Contains 4 hemopexin repeats.

Database links:

Entrez Gene: 118856 Human

Entrez Gene: 214766 Mouse

Entrez Gene: 293573 Rat

Omim: 608416 Human

SwissProt: Q8N119 Human

SwissProt: Q8K3F2 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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