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Rabbit Anti-STEAP2/AP Conjugated antibody (bs-12824R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12824R-AP
英文名稱 Rabbit Anti-STEAP2/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的前列腺跨膜上皮2抗原抗體
別    名 4921538B17Rik; AI930049; IPCA 1; IPCA1; Metalloreductase STEAP2; PCANAP 1; PCANAP1; Prostate cancer associated protein 1; Prostate cancer-associated protein 1; Protein up regulated in metastatic prostate cancer; Protein upregulated in metastatic prostate cancer; PUMPCn; Six transmembrane epithelial antigen of prostate 2; Six transmembrane epithelial antigen of the prostate 2; Six-transmembrane epithelial antigen of prostate 2; SixTransMembrane protein of prostate 1; STAMP 1; STAMP1; STEA2_HUMAN; STEAP 2; STEAP family member 2, metalloreductase; Steap2; STMP; UNQ6507/PRO23203.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human STEAP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Function:
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.

Subcellular Location:
Endosome membrane. Cell membrane.

Tissue Specificity:
Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary.

Similarity:
Belongs to the STEAP family.
Contains 1 ferric oxidoreductase domain.

Database links:

Entrez Gene: 504616 Cow

Entrez Gene: 261729 Human

Entrez Gene: 74051 Mouse

Entrez Gene: 312052. Rat

Omim: 605094 Human

SwissProt: Q8NFT2 Human

SwissProt: Q8BWB6 Mouse

Unigene: 489051 Human

Unigene: 274956 Mouse

Unigene: 203614 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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