產(chǎn)品編號(hào) | bs-24075R-BF350 |
英文名稱 | Rabbit Anti-TBX22/BF350 Conjugated antibody |
中文名稱 | BF350標(biāo)記的TBX22蛋白抗體 |
別 名 | ABERS; CLPA; CPX; D230020M15Rik; dJ795G23.1; T box 22; T box protein 22; T box transcription factor TBX22; T-box protein 22; T-box transcription factor TBX22; Tbx22; TBX22_MOUSE; TBXX. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 發(fā)育生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | Mouse, |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 58kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse TBX22 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis. Subcellular Location: Nucleus. Tissue Specificity: Seems to be expressed at a low level. DISEASE: The disease is caused by mutations affecting the gene represented in this entry. Disease description:A congenital mouth abnormality characterized by fissure of the soft and/or hard palate, due to faulty fusion. Some patients also manifest ankyloglossia, a condition in which movements of the tongue are restricted. Complete ankyloglossia is due to fusion between the tongue and the floor of the mouth. Partial ankyloglossia is due to a short lingual frenum or one which is attached too near the tip of the tongue. Similarity: Contains 1 T-box DNA-binding domain. Database links: Entrez Gene: 50945 Human Entrez Gene: 245572 Mouse Omim: 300307 Human SwissProt: Q9Y458 Human SwissProt: Q8K402 Mouse Unigene: 374253 Human Unigene: 137011 Mouse Unigene: 109981 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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